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DNA damage_Role of SUMO in p53 regulation
Network objects: PIAS1, PIAS2, Ubiquitin, AKT(PKB), MDM2, ...
Description: Role of SUMO in p53 regulation Tumor ...
Development_Thrombopoietin-regulated cell processes
Network objects: AKT(PKB), Cyclin D1, p90RSK2(RPS6KA3), p21, ...
Description: Thrombopoietin-regulated cell processes Thrombopoietin is a hormone ...
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- FREE PATHWAY MAPS
Metabolic maps
Metabolic maps
- Aminoacid metabolism
- Aminoacid metabolism
- Carbohydrates metabolism
- Carbohydrates metabolism
- Lipid metabolism
- Lipid metabolism
- Nucleotide metabolism
- Nucleotide metabolism
- Steroid metabolism
- Steroid metabolism
- Vitamin and cofactor metabolism
- Vitamin and cofactor metabolism
Xenobiotic metabolism
Xenobiotic metabolism
- Regulatory processes
- Regulatory processes
- Apoptosis and survival
- Apoptosis and survival
Apoptosis and survival_APRIL and BAFF signaling- Apoptosis and survival_Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway
- Apoptosis and survival_Anti-apoptotic TNFs/NF-kB/IAP pathway
- Apoptosis and survival_Anti-apoptotic action of membrane-bound ESR1
- Apoptosis and survival_Anti-apoptotic action of nuclear ESR1 and ESR2
- Apoptosis and survival_Apoptotic TNF-family pathways
- Apoptosis and survival_BAD phosphorylation
- Apoptosis and survival_Caspase cascade
- Apoptosis and survival_FAS signaling cascades
- Apoptosis and survival_Lymphotoxin-beta receptor signaling
- Apoptosis and survival_NGF signaling pathway
- Apoptosis and survival_Regulation of Apoptosis by Mitochondrial Proteins
- Apoptosis and survival_Role of CDK5 in neuronal death and survival
- Apoptosis and survival_TNFR1 signaling pathway
- DNA damage_Role of SUMO in p53 regulation
- Development_EPO-induced Jak-STAT pathway
Development_Flt3 signaling
- Cell adhesion
- Cell adhesion
- Cell adhesion_Cadherin-mediated cell adhesion
- Cell adhesion_Cell-matrix glycoconjugates
- Cell adhesion_ECM remodeling
- Cell adhesion_Endothelial cell contacts by junctional mechanisms
- Cell adhesion_Endothelial cell contacts by non-junctional mechanisms
- Cell adhesion_Ephrins signaling
- Cell adhesion_Gap junctions
- Cell adhesion_Integrin inside-out signaling
- Cell adhesion_Integrin-mediated cell adhesion and migration
- Cell adhesion_PLAU signaling
- Cell adhesion_Plasmin signaling
- Cell adhesion_Tight junctions
- Cytoskeleton remodeling_Fibronectin-binding integrins in cell motility
- Cytoskeleton remodeling_Integrin outside-in signaling
- Cytoskeleton remodeling_Reverse signaling by ephrin B
- Development_Slit-Robo signaling
- Neurophysiological process_Receptor-mediated axon growth repulsion
- Cell cycle
- Cell cycle
- Cell cycle_Cell cycle (generic schema)
- Cell cycle_Chromosome condensation in prometaphase
- Cell cycle_ESR1 regulation of G1/S transition
- Cell cycle_Regulation of G1/S transition (part 1)
- Cell cycle_Regulation of G1/S transition (part 2)
- Cell cycle_Role of 14-3-3 proteins in cell cycle regulation
- Cell cycle_Role of APC in cell cycle regulation
- Cell cycle_Role of SCF complex in cell cycle regulation
- Cell cycle_Spindle assembly and chromosome separation
- Cell cycle_Start of DNA replication in early S phase
- Cell cycle_Transition and termination of DNA replication
- DNA damage_ATM/ATR regulation of G1/S checkpoint
- Chemotaxis
- Chemotaxis
- Cytoskeleton remodeling
- Cytoskeleton remodeling
- Cytoskeleton remodeling_CDC42 in cellular processes
- Cytoskeleton remodeling_FAK signaling
- Cytoskeleton remodeling_Fibronectin-binding integrins in cell motility
- Cytoskeleton remodeling_Integrin outside-in signaling
- Cytoskeleton remodeling_Keratin filaments
- Cytoskeleton remodeling_Neurofilaments
- Cytoskeleton remodeling_RalA regulation pathway
- Cytoskeleton remodeling_RalB regulation pathway
- Cytoskeleton remodeling_Regulation of actin cytoskeleton by Rho GTPases
- Cytoskeleton remodeling_Reverse signaling by ephrin B
- Cytoskeleton remodeling_Role of PDGFs in cell migration
- Cytoskeleton remodeling_Role of PKA in cytoskeleton reorganisation
- Development_Slit-Robo signaling
- G-protein signaling_RAC1 in cellular process
- G-protein signaling_RhoA regulation pathway
- G-protein signaling_RhoB regulation pathway
- Neurophysiological process_Receptor-mediated axon growth repulsion
- Development
- Development
- Development (common pathways)
- Development (common pathways)
- Cell cycle_ESR1 regulation of G1/S transition
- Cytoskeleton remodeling_FAK signaling
- Development_A1 receptor signaling
- Development_A2A receptor signaling
- Development_A2B receptor: action via G-protein alpha s
- Development_A3 receptor signaling
- Development_ACM2 and ACM4 activation of ERK
- Development_Activation of ERK by Alpha-1 adrenergic receptors
- Development_Alpha-2 adrenergic receptor activation of ERK
- Development_Beta-adrenergic receptors regulation of ERK
- Development_Beta-adrenergic receptors signaling via cAMP
- Development_EDNRB signaling
- Development_Endothelin-1/EDNRA signaling
- Development_Endothelin-1/EDNRA transactivation of EGFR
- Development_FGF-family signaling
- Development_FGFR signaling pathway
- Development_G-Proteins mediated regulation MARK-ERK signaling
- Development_Glucocorticoid receptor signaling
- Development_Growth hormone signaling via PI3K/AKT and MAPK cascades
- Development_HGF signaling pathway
- Development_Hedgehog and PTH signaling pathways in bone and cartilage development
- Development_IGF-1 receptor signaling
- Development_Leptin signaling via JAK/STAT and MAPK cascades
- Development_Leptin signaling via PI3K-dependent pathway
- Development_Ligand-dependent activation of the ESR1/AP-1 pathway
- Development_Ligand-independent activation of ESR1 and ESR2
- Development_NOTCH1-mediated pathway for NF-KB activity modulation
- Development_Notch Signaling Pathway
- Development_PDGF signaling via MAPK cascades
- Development_PDGF signaling via STATs and NF-kB
- Development_Prolactin receptor signaling
- Development_Role of Activin A in cell differentiation and proliferation
- Development_TGF-beta receptor signaling
- Signal transduction_Activin A signaling regulation
- Angiogenesis
- Angiogenesis
- Development_Angiopoietin - Tie2 signaling
- Development_Angiotensin activation of ERK
- Development_Angiotensin signaling via PYK2
- Development_Angiotensin signaling via beta-Arrestin
- Development_VEGF signaling and activation
- Development_VEGF signaling via VEGFR2 - generic cascades
- Development_VEGF-family signaling
- Epidermal cell development
- Epidermal cell development
- Hemopoiesis
- Hemopoiesis
- Immune system development
- Immune system development
- Immune response_Function of MEF2 in T lymphocytes
- Immune response_IL-12 signaling pathway
- Immune response_IL-12-induced IFN-gamma production
- Immune response_IL-2 activation and signaling pathway
- Immune response_IL-23 signaling pathway
- Immune response_IL-3 activation and signaling pathway
- Immune response_IL-4 signaling pathway
- Immune response_IL-9 signaling pathway
- Myogenesis
- Myogenesis
- Neurogenesis
- Neurogenesis
- Apoptosis and survival_NGF signaling pathway
- Apoptosis and survival_Role of CDK5 in neuronal death and survival
- Cytoskeleton remodeling_Reverse signaling by ephrin B
- Development_CNTF receptor signaling
- Development_Dopamine D2 receptor transactivation of EGFR
- Development_GDNF family signaling
- Development_MAG-dependent inhibition of neurite outgrowth
- Development_Neurotrophin family signaling
- Development_Slit-Robo signaling
- Neurophysiological process_Receptor-mediated axon growth repulsion
- DNA-damage
- DNA-damage
- Immune response
- Immune response
- Immune response _CCR3 signaling in eosinophils
- Immune response _ICOS pathway in T-helper cell
- Immune response _T cell receptor signaling pathway
- Immune response_Antigen presentation by MHC class I
- Immune response_Antigen presentation by MHC class II
- Immune response_BCR pathway
- Immune response_CD16 signaling in NK cells
- Immune response_CD28 signaling
- Immune response_Fc epsilon RI pathway
- Immune response_Function of MEF2 in T lymphocytes
- Immune response_IFN alpha/beta signaling pathway
- Immune response_IL-10 signaling pathway
- Immune response_IL-12 signaling pathway
- Immune response_IL-12-induced IFN-gamma production
- Immune response_IL-2 activation and signaling pathway
- Immune response_IL-22 signaling pathway
- Immune response_IL-23 signaling pathway
- Immune response_IL-3 activation and signaling pathway
- Immune response_IL-4 signaling pathway
- Immune response_IL-9 signaling pathway
- Immune response_MIF-JAB1 signaling
- Immune response_NFAT in immune response
- Immune response_Role of DAP12 receptors in NK cells
- Immune response_Role of TLRs 3 and 4 in cell antiviral response: TICAM1-specific signaling pathways
- Immune response_Role of integrins in NK cells cytotoxicity
- Neurophysiological process_PGE2-induced pain processing
- Acute inflammatory response
- Acute inflammatory response
- Apoptosis and survival_Lymphotoxin-beta receptor signaling
- Apoptosis and survival_TNFR1 signaling pathway
- Immune response _MIF-mediated glucocorticoid regulation
- Immune response_Alternative complement pathway
- Immune response_Classical complement pathway
- Immune response_IFN gamma signaling pathway
- Immune response_IL-1 signaling pathway
- Immune response_IL-6 signaling pathway
- Immune response_Lectin induced complement pathway
- Immune response_MIF in innate immunity response
- Immune response_TLR signaling pathways
- Signal transduction_JNK pathway
- Transcription_NF-kB signaling pathway
- Immune response: organism-specific maps for Mouse, Rat and Human
- Immune response: organism-specific maps for Mouse, Rat and Human
- Muscle contraction
- Muscle contraction
- Neurophysiological process
- Neurophysiological process
- Hypoxia response
- Hypoxia response
- Oxidative stress
- Oxidative stress
- Proteolysis
- Proteolysis
- Transcription
- Transcription
- Translation
- Translation
- Transport
- Transport
- Protein function
- Protein function
- Cyto/chemokines
- Cyto/chemokines
- Chemotaxis_CXCR4 signaling pathway
- Development_CNTF receptor signaling
- Immune response _CCR3 signaling in eosinophils
- Immune response_IFN alpha/beta signaling pathway
- Immune response_IFN gamma signaling pathway
- Immune response_IL-1 signaling pathway
- Immune response_IL-10 signaling pathway
- Immune response_IL-12 signaling pathway
- Immune response_IL-12-induced IFN-gamma production
- Immune response_IL-2 activation and signaling pathway
- Immune response_IL-22 signaling pathway
- Immune response_IL-23 signaling pathway
- Immune response_IL-3 activation and signaling pathway
- Immune response_IL-4 signaling pathway
- Immune response_IL-6 signaling pathway
- Immune response_IL-9 signaling pathway
- Immune response_Oncostatin M signaling via JAK-Stat in human cells
- Immune response_Oncostatin M signaling via MAPK in human cells
- GPCR
- GPCR
- Chemotaxis_CXCR4 signaling pathway
- Development_A1 receptor signaling
- Development_A2A receptor signaling
- Development_A2B receptor: action via G-protein alpha s
- Development_A3 receptor signaling
- Development_ACM2 and ACM4 activation of ERK
- Development_Activation of ERK by Alpha-1 adrenergic receptors
- Development_Alpha-2 adrenergic receptor activation of ERK
- Development_Angiotensin activation of ERK
- Development_Angiotensin signaling via PYK2
- Development_Angiotensin signaling via beta-Arrestin
- Development_Beta-adrenergic receptors regulation of ERK
- Development_Beta-adrenergic receptors signaling via cAMP
- Development_Dopamine D2 receptor transactivation of EGFR
- Development_EDNRB signaling
- Development_Endothelin-1/EDNRA signaling
- Development_Endothelin-1/EDNRA transactivation of EGFR
- Development_G-Proteins mediated regulation MARK-ERK signaling
- G-protein signaling_G-Protein alpha-12 signaling pathway
- G-protein signaling_G-Protein alpha-i signaling cascades
- G-protein signaling_G-Protein alpha-q signaling cascades
- G-protein signaling_G-Protein alpha-s signaling cascades
- G-protein signaling_G-Protein beta/gamma signaling cascades
- G-protein signaling_Regulation of p38 and JNK signaling mediated by G-proteins
- Immune response _CCR3 signaling in eosinophils
- Neurophysiological process_Glutamate regulation of Dopamine D1A receptor signaling
- Signal transduction_Activation of PKC via G-Protein coupled receptor
- Signal transduction_PKA signaling
- Signal transduction_cAMP signaling
- Transcription_Transcription factor Tubby signaling pathways
- Translation_Translation regulation by Alpha-1 adrenergic receptors
- RAS-group
- RAS-group
- Cytoskeleton remodeling_CDC42 in cellular processes
- Cytoskeleton remodeling_RalA regulation pathway
- Cytoskeleton remodeling_RalB regulation pathway
- Cytoskeleton remodeling_Regulation of actin cytoskeleton by Rho GTPases
- Development_EGFR signaling via small GTPases
- G-protein signaling_Cross-talk between Ras-family GTPases
- G-protein signaling_H-RAS regulation pathway
- G-protein signaling_K-RAS regulation pathway
- G-protein signaling_M-RAS regulation pathway
- G-protein signaling_N-RAS regulation pathway
- G-protein signaling_RAC1 in cellular process
- G-protein signaling_Rac2 regulation pathway
- G-protein signaling_Rap1A regulation pathway
- G-protein signaling_Rap1B regulation pathway
- G-protein signaling_Rap2B regulation pathway
- G-protein signaling_Ras family GTPases in kinase cascades (scheme)
- G-protein signaling_Regulation of CDC42 activity
- G-protein signaling_Regulation of RAC1 activity
- G-protein signaling_RhoA regulation pathway
- G-protein signaling_RhoB regulation pathway
- G-protein signaling_TC21 regulation pathway
- Growth factors
- Growth factors
- Apoptosis and survival_NGF signaling pathway
- Cytoskeleton remodeling_Role of PDGFs in cell migration
- Development_EGFR signaling pathway
- Development_EGFR signaling via PIP3
- Development_EGFR signaling via small GTPases
- Development_EPO-induced MAPK pathway
- Development_ERBB-family signaling
- Development_Endothelin-1/EDNRA transactivation of EGFR
- Development_FGF-family signaling
- Development_FGFR signaling pathway
- Development_Flt3 signaling
- Development_HGF signaling pathway
- Development_IGF-1 receptor signaling
- Development_Ligand-independent activation of ESR1 and ESR2
- Development_MAG-dependent inhibition of neurite outgrowth
- Development_Neurotrophin family signaling
- Development_PDGF signaling via MAPK cascades
- Development_PDGF signaling via STATs and NF-kB
- Development_Prolactin receptor signaling
- Development_Role of Activin A in cell differentiation and proliferation
- Development_TGF-beta receptor signaling
- Development_Thrombopoietin-regulated cell processes
- Development_VEGF signaling and activation
- Development_VEGF signaling via VEGFR2 - generic cascades
- Development_VEGF-family signaling
- Hormones
- Hormones
- Apoptosis and survival_Anti-apoptotic action of membrane-bound ESR1
- Apoptosis and survival_Anti-apoptotic action of nuclear ESR1 and ESR2
- Cell cycle_ESR1 regulation of G1/S transition
- Development_EDNRB signaling
- Development_Endothelin-1/EDNRA signaling
- Development_Endothelin-1/EDNRA transactivation of EGFR
- Development_Glucocorticoid receptor signaling
- Development_Growth hormone signaling via PI3K/AKT and MAPK cascades
- Development_Leptin signaling via JAK/STAT and MAPK cascades
- Development_Leptin signaling via PI3K-dependent pathway
- Development_Ligand-dependent activation of the ESR1/AP-1 pathway
- Development_Ligand-independent activation of ESR1 and ESR2
- Development_Prolactin receptor signaling
- Regulation of lipid metabolism_Insulin signaling:generic cascades
- Signal transduction_Activin A signaling regulation
- Transcription_Androgen Receptor nuclear signaling
- Transcription_Ligand-dependent activation of the ESR1/SP pathway
- Translation_Insulin regulation of translation
- Translation_Non-genomic (rapid) action of Androgen Receptor
- Kinases
- Kinases
- Cytoskeleton remodeling_FAK signaling
- Cytoskeleton remodeling_Role of PKA in cytoskeleton reorganisation
- Signal transduction_AKT signaling
- Signal transduction_Activation of PKC via G-Protein coupled receptor
- Signal transduction_Erk Interactions: Inhibition of Erk
- Signal transduction_JNK pathway
- Signal transduction_PKA signaling
- Phosphatases
- Phosphatases
- Second messenger
- Second messenger
- Transcription factors
- Transcription factors
- Development_Glucocorticoid receptor signaling
- Development_Ligand-dependent activation of the ESR1/AP-1 pathway
- Development_Ligand-independent activation of ESR1 and ESR2
- Development_NOTCH1-mediated pathway for NF-KB activity modulation
- Development_Role of HDAC and calcium/calmodulin-dependent kinase (CaMK) in control of skeletal myogenesis
- Immune response_Function of MEF2 in T lymphocytes
- Immune response_NFAT in immune response
- Transcription_Androgen Receptor nuclear signaling
- Transcription_CREB pathway
- Transcription_CREM signaling in testis
- Transcription_Ligand-Dependent Transcription of Retinoid-Target genes
- Transcription_Ligand-dependent activation of the ESR1/SP pathway
- Transcription_NF-kB signaling pathway
- Transcription_P53 signaling pathway
- Transcription_PPAR Pathway
- Transcription_Receptor-mediated HIF regulation
- Transcription_Role of VDR in regulation of genes involved in osteoporosis
- Transcription_Transcription factor Tubby signaling pathways
- Regulation of metabolism
- Regulation of metabolism
- Regulation of lipid metabolism
- Regulation of lipid metabolism
- Disease maps
- Disease maps
- Cardiovascular Diseases
- Cardiovascular Diseases
- Cardiac Hypertrophy
- Cardiac Hypertrophy
- Lung Diseases
- Lung Diseases
- Cystic Fibrosis
- Cystic Fibrosis
- Bacterial infections in CF airways
- Beta-2 adrenergic-dependent CFTR expression
- CFTR folding and maturation (norm and CF)
- CFTR translational fidelity (class I mutations)
- CFTR-dependent regulation of ion channels in Airway Epithelium (norm and CF)
- Cholesterol and Sphingolipids transport / Distribution to the intracellular membrane compartments (normal and CF)
- Cholesterol and Sphingolipids transport / Generic schema (normal and CF)
- Cholesterol and Sphingolipids transport / Influx to the early endosome in lung (normal and CF)
- Cholesterol and Sphingolipids transport / Recycling to plasma membrane in lung (normal and CF)
- Cholesterol and Sphingolipids transport / Transport from Golgi and ER to the apical membrane (normal and CF)
- Cytokine production by Th17 cells in CF
- Cytokine production by Th17 cells in CF (Mouse model)
- Delta508-CFTR traffic / ER-to-Golgi in CF
- Delta508-CFTR traffic / Sorting endosome formation in CF
- IL-1 beta-dependent CFTR expression
- Immune response_Antigen presentation by MHC class I
- Immune response_Bacterial infections in normal airways
- Inhibitory action of Lipoxin A4 on PDGF, EGF and LTD4 signaling
- Inhibitory action of Lipoxins and Resolvin E1 on neutrophil functions
- Inhibitory action of Lipoxins on Superoxide production in neutrophils
- Inhibitory action of Lipoxins on neutrophil migration
- Mechanisms of CFTR activation by S-nitrosoglutathione (normal and CF)
- Mucin expression in CF via IL-6, IL-17 signaling pathways
- Mucin expression in CF via TLRs, EGFR signaling pathways
- NO-dependent CFTR activation (normal and CF)
- Normal wtCFTR traffic / ER-to-Golgi
- Normal wtCFTR traffic / Sorting endosome formation
- Regulation of CFTR activity (norm and CF)
- Regulation of CFTR gating (normal and CF)
- Regulation of degradation of deltaF508 CFTR in CF
- Regulation of degradation of wt-CFTR
- Transport_Clathrin-coated vesicle cycle
- wtCFTR and delta508 traffic / Clathrin coated vesicles formation (norm and CF)
- wtCFTR and delta508-CFTR traffic / Generic schema (norm and CF)
- wtCFTR and deltaF508 traffic / Late endosome and Lysosome (norm and CF)
- wtCFTR and deltaF508 traffic / Membrane expression (norm and CF)
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